1. S.-Y. Lin, S.-C. Tang*, C.-H. Kuo, C.-H. Chen, Y.-C. Chao, C.-F. Huang, J.-S. Jeng. The association between direct oral anticoagulant concentration upon acute stroke and stroke outcome. European Journal of Internal Medicine, 2023, 113(2023), 31-37.

2. S.-Y. Lin, S.-C. Tang*, C.-H. Kuo, L.-T. Ho, Y.-B. Liu, Y.-F. Peng, L.-K. Tsai, C.-F. Huang, J.-S. Jeng. Impact of Direct Oral Anticoagulant Concentration on Clinical Outcomes in Asian Patients with Atrial Fibrillation. Clinical Pharmacology & Therapeutics, 2023, 114(1), 230-238.

3. D.-M.Tsai, C.-Y. Chang, S.-M. Lin, T.-C. Kuo, S.-Y. Wang, G.-Y. Chen, C.-H. Kuo, Y. J. Tseng*. MetaMOPE: a web service for mobile phase determination and fast chromatography peaks evaluation for metabolomics. Bioinformatics Advances, 2023, 3(1), vbad061.

4. S.-Y. Lin, Y.-B. Liu, L.-T. Ho, Y.-F. Peng, C.-H. Kuo, S.-C. Tang, C.-F. Huang, J.-S. Jeng. Impact of amiodarone on plasma concentration of direct oral anticoagulant in patients with atrial fibrillation. Journal of the Formosan Medical Association, 2023 , DOI:10.1016/j.jfma.2023.02.012.

5. T.-H. Lee, C.-N. Cheng, C.-W. Lee, C.-H. Kuo, S.-C. Tang, J.-S. Jeng. Investigating sphingolipids as biomarkers for the outcomes of acute ischemic stroke patients receiving endovascular treatment. Journal of the Formosan Medical Association, 2023, 122(1), 19-28.

6. Y.-T. Lin, S.-A. Chan, Y.-J. Chen, K.-P. Chung*, C.-H. Kuo*. Using an in-sample addition of medronic acid for the analysis of purine- and pyrimidine-related derivatives and its application in the study of lung adenocarcinoma a549 cell lines by lc-ms/ms. Journal of Proteome Research, 2023, 22(5), 1434-1445

7. C.-N. Cheng, Y.-F. Peng, J.-Y. Chen, G.-Y. Chen, T.-I Weng, C.-H. Kuo. Development of the dried blood spot preparation protocol for comprehensive evaluation of the hematocrit effect. Analytica Chimica Acta, 2023, 1239, 340650.

8. J.-Y. Chen, G.-Y. Chen, H.-N. Ong, M.-L. Lai, Y.-J. Ho, C.-H. Kuo, T.-I Weng. Defective determination of synthetic cathinones in blood for forensic investigation. Clinica Chimica Acta, 2023, 539, 122-129.

9. H.-W. Liao, Y.-W. Cheng, S.-C. Tang, C.-H. Kuo. Bias caused by incomplete metabolite extraction and matrix effect: Evaluation of critical factors for plasma sample preparation prior to metabolomics. Journal of Pharmaceutical and Biomedical Analysis, 2022, 219:114930.

10. C.-H. Lin, S.-J. Chen, C.-H. Kuo. Author Response: Association of Fecal and Plasma Levels of Short-Chain Fatty Acids With Gut Microbiota and Clinical Severity in Patients With Parkinson Disease. Neurology, 2022, 99(9) , 404.

11. M.-S. Wu, D.-S. Han, W.-k. Wu, P.-Y. Liu, Y.-T. Yang, H.-C. Hsu, C.-H. Kuo, T.-G. Wang. Differences in the gut microbiome and reduced fecal butyrate in elders with low skeletal muscle mass. Clinical Nutrition, 2022, 41(7), 1491-1500.

12. S.-J. Chen, C.-C. Chen, H.-Y. Liao, Y.-W. Wu, J.-M. Liou, M.-S. Wu, C.-H. Kuo, C.-H. Lin. Alteration of Gut Microbial Metabolites in the Systemic Circulation of Patients with Parkinson’s Disease. Journal of Parkinson's Disease, 2022, 12(4), 1219-1230.

13. S.-Y. Lin, C.-H. Kuo, L.-T. Ho, Y.-B. Liu, C.-F. Huang, S.-C. Tang, J.-S. Jeng. Association Between Apixaban Concentration and Clinical Outcomes in Asians With Atrial Fibrillation. Circulation: Arrhythmia and Electrophysiology, 2022, 15(5), e010693.

14. H.-H. Chiu, Y.-J. Tsai, C. Lo, C.-H. Lin, I.-L. Tsai, C.-H. Kuo. Development of an efficient mAb quantification assay by LC-MS/MS using rapid on-bead digestion. Analytica Chimica Acta, 2022, 1193, 339319 .

15. H.-H. Chiu, Y.-J. Tsai, C. Lo, H.-W. Liao, C.-H. Lin, S.-C. Tang, C.-H. Kuo. Development of an LC-MS/MS method to simultaneously quantify therapeutic mAbs and estimate hematocrit values in dried blood spot samples. Analytica Chimica Acta, 2022, 1189, 339231.

16. J.-S. Tsai, S.-Y. Wang, C.-H. Chang, C.-Y. Chen, C.-J. Wen, G.-Y. Chen, C.-H. Kuo, Y. J. Tseng, C.-Y. Chen. Identification of traumatic acid as a potential plasma biomarker for sarcopenia using a metabolomics-based approach. Journal of Cachexia, Sarcopenia and Muscle, 2022, 13(1), 276-286.

17. S.-J. Chen, C.-C. Chen, H.-Y. Liao, Y.-T. Lin, Y.-W. Wu, J.-M. Liou, M.-S. Wu, C.-H. Kuo, C.-H. Lin. Association of Fecal and Plasma Levels of Short-Chain Fatty Acids With Gut Microbiota and Clinical Severity in Patients With Parkinson Disease. Neurology, 2022, 98(8), e848-e858.

18. Y.-J. Chou, K. M. Kober, K.-H. Yeh, B. A. Cooper, C.-H. Kuo, B.-R. Lin, T.-C. Kuo, Y. J. Tseng, C. Miaskowski, S.-C. Shun. A pilot study of metabolomic pathways associated with fatigue in patients with colorectal cancer receiving chemotherapy. European Journal of Oncology Nursing, 2022, 56, 102096.

19. C.-H. Ma, H.-Y. Chan, M. H. Hsieh, C.-C. Liu, C.-M. Liu, H.-G. Hwu, C.-H. Kuo, W. J. Chen, T.-J. Hwang. Identifying dopamine supersensitivity through a randomized controlled study of switching to aripiprazole from other antipsychotic agents in patients with schizophrenia. Therapeutic Advances in Psychopharmacology, 2022, 12, 1-10.

20. T.-H. Lee, C.-N. Cheng, H.-C. Chao, C.-H. Lee, C.-H. Kuo, S.-C. Tang, J.-S. Jeng. Plasma ceramides are associated with outcomes in acute ischemic stroke patients. Journal of the Formosan Medical Association, 2022, 121(1 Pt 1), 43-50.

21. S.-Y. Lin, C.-H. Kuo, T.-M. Huang, Y.-F. Peng, C.-F. Huang, S.-C. Tang, J.-S. Jeng. Impact of different renal function equations on direct oral anticoagulant concentrations. Scientific Reports, 2021, 11(1), 23833.

22. B.-H. Liou, C.-N. Cheng, Y.-T. Lin, Y.-J. Lin, Y.-C. Chuang , K.-Y. Lin, W.-C. Liu, S.-W. Lin, C.-H. Kuo, H.-Y. Sun, C.-C. Hung (2021, Nov). Short-course daily isoniazid and rifapentine for latent tuberculosis infection in people living with HIV who received coformulated bictegravir/emtricitabine/tenofovir alafenamide. Journal of the International AIDS Society, 2021, 24(11): e25844.

23. C.-H. Lee, S.-C. Tang, C.-H. Kuo (2021, Nov). Differentiating ether phosphatidylcholines with a collision energy-optimized MRM method by RPLCMS/MS and its application to studying ischemia-neuronal injury. Analytica Chimica Acta, 2021, 1184:339014.

24. C.-H. S. Chen, T.-C. Kuo, H.-C. Kuo, Y. J. Tseng, C.-H. kuo, T.-H. Yuan, C.-C. Chan. Lipidomics of children and adolescents exposed to multiple industrial pollutants. Environmental Research, 2021, 201(2021): 111448.

25. K.-Y. Chen, S.-Y. Lin, C.-N. Lee, H.-T. Wu, C.-H. Kuo, H.-C. Kuo, C.-C. Chuang, C.-H. Kuo, S.-C. Chen, K.-C. Fan, M.-W. Lin, C.-T. Fang, H.-Y. Li. Maternal Plasma Lipids During Pregnancy, Insulin-like Growth Factor-1, and Excess Fetal Growth. The Journal of Clinical Endocrinology & Metabolism, 2021, 106(9), e3461-e3472.

26. S.-Y. Lin, C.-H. Kuo, L.-T. Ho, Y.-B. Liu, C.-F. Huang, S.-C. Tang, J.-S. Jeng . Factors Associated With Edoxaban Concentration Among Patients With Atrial Fibrillation. Frontiers in Pharmacology, 2021, 17: 736826.

27. T.-H. Lee, C.-H. Kuo*, S.-C. Tang*. Author Reply to letter to the editor "Plasma ceramides are associated with outcomes in acute ischemic stroke patients", Journal of the Formosan Medical Association, 2021, 120(8): 1661-1662.

28. Y.-Y. Hsiao, Y.-C. Huang, S.-Y. Chang, C.-H. Kuo, S.-F. Chang, Y.-T. Lin, Y.-Z.Luo, Y.-L. Lee, C.-C. Hung. Failure of pre-exposure prophylaxis with on-demand tenofovir disoproxil fumarate/emtricitabine resulting in emergence of antiretroviral resistance, Journal of Microbiology, Immunology and Infection, 2021, 54(4):755-757.

29. H.-Y. Liao, C.-Y. Wang, C.-H. Lee, H.-L. Kao, W.-K. Wu*, C.-H. Kuo*. Development of an Efficient and Sensitive Chemical Derivatization-Based LC–MS/MS Method for Quantifying Gut Microbiota-Derived Metabolites in Human Plasma and Its Application in Studying Cardiovascular Disease, Journal of Proteome Research, 2021, 20 (7): 3508-3518.

30. W.-D. Liu, C.-N Cheng, Y.-T. Lin, C.-H. Kuo, S.-Y. Ho, C.-C. Hung*. Acute HIV infection with presentations mimicking acalculous cholecystitis A case report. Medicine, 100(28), e26653.

31. S.-Y. Lin, Y.-F. Peng, C.-F. Huang, C.-H. Kuo*, S.-C. Tang, J.-S. Jeng. Measurement of Dabigatran Concentration Using Finger Prick Dried Blood Spot Sample Collection, Frontiers in Pharmacology, 2021, 12: 679431.

32. F.-Y. Tzou, T.-Y. Su, W.-S. Lin, H.-C. Kuo, Y-L. Yu, Y.-H. Yeh, C.-C. Liu, C.-H. Kuo, S.-Y. Huang, C.-C. Chan. Dihydroceramide desaturase regulates the compartmentalization of Rac1 for neuronal oxidative stress, Cell Reports, 2021, 35(2):108972.

33. J.-W. Huang, C.-H. Kuo, H.-C. Kuo, J.-Y. Shih, T.-W. Tsai, L.-C. Chang*. Differences in Fatty Acid Oxidation between Nab-Paclitaxel- and Solvent- Based Paclitaxel-Treated A549 Cells Based on Metabolomics, ACS Omega, 2021, 6 (8): 5138-5145.

34. J.-W. Huang, C.-H. Kuo, H.-C. Kuo, J.-Y. Shih, T.-W. Tsai, L.-C. Chang. Cell metabolomics analyses revealed a role of altered fatty acid oxidation in neurotoxicity pattern difference between nab-paclitaxel and solvent-based paclitaxel, PLoS One, 2021, 16 (3): e0248942.

35. W.-H. Lu, H.-H.Chiu, H.-C. Kuo, G.-Y. Chen, D. Chepyala, C.-H. Kuo*. Using matrix-induced ion suppression combined with LC-MS/MS for quantification of trimethylamine-N-oxide, choline, carnitine and acetylcarnitine in dried blood spot samples, Analytica Chimica Acta , 2021, 1149: 338214.

36. C.-N. Cheng, C.-C. Wu, C.-H. Kuo, C.-C. Wang, J.-T. Wang, Y.-T. Lin, R.-S. Jhang, S.-W. Lin*. Impact of high plasma concentrations of linezolid in Taiwanese adult patients- therapeutic drug monitoring in improving adverse drug reactions, Journal of the Formosan Medical Association, 2021, 120 (1 Pt 2): 466-475.

37. Y.-J. Chou, K. M. Kober, C.-H. Kuo, K.-H. Yeh, T.-C. Kuo, Y.-J. Tseng, C. Miaskowski, J.-T. Liang, S.-C. Shun*. A Pilot Study of Metabolomic Pathways Associated With Fatigue in Survivors of Colorectal Cancer, Biological Research for Nursing, 2021, 23 (1): 42-49.

38. S.-J. Chen, C.-H. Kuo, H.-C. Kuo, C.-C. Chen, W.-K. Wu, J.-M. Liou, M.-S. Wu, C.-H. Lin*. The Gut Metabolite Trimethylamine N-Oxide Is Associated With Parkinson's Disease Severity and Progression, Movement Disorders, 2020, 35 (11): 2115-2116.

39. W.-K. Wu, S. Panyod, P.-Y. Liu, C.-C. Chen, H.-L. Kao, H.-L. Chuang, Y.-H. Chen, H.-B. Zou, H.-C. Kuo, C.-H. Kuo, B.-Y. Liao, H.-T. Chiu, C.-H. Chung, Y.-C. Lin, Y.-C. Lee, S.-L. Tang, J.-T. Wang, Y.-W. Wu, C.-C. Hsu, L.-Y. Sheen, A. Orekhov, M.-S. Wu. Characterization of TMAO productivity from carnitine challenge facilitates personalized nutrition and microbiome signatures discovery, Microbiome, 2020, 8(1):162.

40. Y.-W. Jen, T.-J. Hwang, H.-Y. Chan, M. H Hsieh, C.-C. Liu, C.-M. Liu, H.-G. Hwu, C.-H. Kuo, Y.-T. Lin, Y.-L. Chien, W. J Chen. Abnormally low prolactin levels in schizophrenia patients after switching to aripiprazole in a randomized trial: a biomarker for rebound in psychotic symptoms?, BMC Psychiatry, 2020, 20(1):552.

41. M.- S. Tsai, S.-H. Chang, W.-H. Kuo, C.-H. Kuo, S.-Y. Li, M.-Y. Wang, D.-Y. Chang, Y.-S. Lu, C.-S. Huang, A.-L. Cheng, C.-H. Lin*, P. -C. Chen*. A case-control study of perfluoroalkyl substances and the risk of breast cancer in Taiwanese women, Environment International, 2020, 142: 105850.

42. S.-L. Wu, C.-N. Cheng, C.-C. Wang, S.-W. Lin*, C.-H. Kuo*. Metabolomics analysis of plasma reveals voriconazole-induced hepatotoxicity is associated with oxidative stress, Toxicology and Applied Pharmacology, 2020, 403: 115157.

43. C. Lo, Y.-L. Hsu, C.-N. Cheng, C.- H. Lin, H.-C. Kuo, C.-S. Huang*, C.-H. Kuo*. Investigating the Association of the Biogenic Amine Profile in Urine with Therapeutic Response to Neoadjuvant Chemotherapy in Breast Cancer Patients, Journal of Proteome Research, 2020, 19 (10): 4061-4070.

44. C.-C. Hsieh*, H.-H. Chiu, C.-H. Wang, C.-H. Kuo. Aspirin Modifies Inflammatory Mediators and Metabolomic Profiles and Contributes to the Suppression of Obesity-Associated Breast Cancer Cell Growth, International Journal of Molecular Sciences, 2020, 21 (13): 4652.

45. G.-J. Chen, S.-W. Lin, I.-L. Tsai, C.-H. Kuo, J.-T. Wang, S.-M. Hsieh*. Therapeutic drug monitoring of the teicoplanin trough level after the loading doses in patients receiving venoarterial extracorporeal membrane oxygenation, Journal of the Formosan Medical Association, 2020, 119 (6): 1086-1092.

46. S.-W. Lin, C.-H. Kuo, L.-J. Shen, Y.-C. Chen, C.-C. Hung, F.-L. Lin Wu. Implementation and outcomes of a therapeutic drug monitoring program for antifungal and antiretroviral agents in a tertiary medical center in Taiwan, JACCP Journal of the American College of Clinical Pharmacy, 2020, 3(5): 905-912.

47. M. Huang, H.-Y. Li, H.-W. Liao, C.-H. Lin, C.-Y. Wang, W.-H. Kuo, C.-H. Kuo. Using post-column infused internal standard assisted quantitative metabolomics for establishing prediction models for breast cancer detection, Rapid Communications in Mass Spectrometr, 2020, 34(S1):e8581.

48. R.-S. Jhang, S.-Y. Lin, Y.-F. Peng, H.-C. Chao, I-L. Tsai, Y.-T. Lin, H. –W. Liao, S.-C. Tang*, C.-H. Kuo*, J.-S. Jeng. Using the PCI-IS Method to Simultaneously Estimate Blood Volume and Quantify Nonvitamin K Antagonist Oral Anticoagulant Concentrations in Dried Blood Spots, Analytical Chemistry, 2020, 92: 2511-2518.

49. H.-H. Chiu, C.-H. Kuo*. Gas chromatography-mass spectrometry- based analytical strategies for fatty acid analysis in biological samples, Journal of Food and Drug Analysis, 2020, 28 (1): 60-73.

50. H.-W. Liao*, C.-H. Kuo, H.-C. Chao, G.-Y. Chen. Post-column infused internal standard assisted lipidomics profiling strategy and its application on phosphatidylcholine research, Journal of Pharmaceutical and Biomedical Analysis, 2020, 178:112956.

51. S.-Y. Lin, C.-H. Kuo, S.-J. Yeh, L.-K. Tsai, Y.-B. Liu, C.-F. Huang, S.-C. Tang*, J.-S. Jeng. Real World Rivaroxaban and Apixaban Levels in Asian Patients with Atrial Fibrillation, Clinical Pharmacology and Therapeutics , 2020, 107(1):278-286.

52. T.-C. Kuo, C.-E. Tan, S.-Y. Wang, O. A. Lin, B.-H. Su, M.-T. Hsu, J. Lin, Y.-Y. Cheng, C.-S. Chen, Y.-C. Yang, K.-H. Chen, S.-W. Lin, C.-C. Ho, C.-H. Kuo, Y.-J. Tseng*. Human Breathomics Database. Database (Oxford), 2020, baz139.

53. C.-C. Wu, C.-H. Tai, W.-Y. Liao, C.-C. Wang, C.-H.Kuo, S.-W. Lin,S.-C. Ku*. Augmented Renal Clearance Is Associated with Inadequate Antibiotic Pharmacokinetic/Pharmacodynamic Target in Asian ICU Population: A Prospective Observational Study, Infection and Drug Resistance, 2019, 12: 2531-2541.

54. Cheng, Y.-W., Chen, K.-W., Kuo, H.-C., Kuo, C.-H., Lin, W.-H., Chen, P.-J., Yeh, S.-H*. Specific diacylglycerols generated by hepatic lipogenesis stimulate the oncogenic androgen receptor activity in male hepatocytes, International Journal Of Obesity, 2019, 43(12): 2469–2479.

55. S.-L. Wu, T.-Y. Wei, S.-W. Lin, K.-Y. Su, C.-H. Kuo*. Metabolomics Investigation of Voriconazole-Induced Hepatotoxicity in Mice, Chemical Research in Toxicology, 2019, 32(9): 1840-1849.

56. W.-H. Hsu, C.-H. Lee, Y.-M. Chao, C.-H. Kuo, W.-C. Ku, C.-C. Chen*, Y.-L. Lin*. ASIC3-dependent metabolomics profiling of serum and urine in a mouse model of fibromyalgia, Scientific Reports, 2019, 9(1): 12123.

57. D. Chepyala, H.-C. Kuo, K.-Y. Su, H.-W. Liao, S.-Y. Wang, S. R. Chepyala, L.- C.Chang*,C.-H.Kuo*. Improved Dried Blood Spot-Based Metabolomics Analysis by a Postcolumn Infused-Internal Standard Assisted Liquid Chromatography-Electrospray Ionization Mass Spectrometry Method, Analytical Chemistry , 2019, 91 (16): 10702–10712.

58. H.-C. Chao, T.-H. Lee, C.-S. Chiang, S.-Y. Yang, C.-H Kuo*, S.-C. Tang*. Sphingolipidomics Investigation of the Temporal Dynamics after Ischemic Brain Injury, Journal of Proteome Research, 2019, 18(9): 3470-3478.

59. S.-Y. Lin, S.-C. Tang*, C.-H. Kuo, L.-K. Tsai, S.-J. Yeh, L.-J. Shen, J.-S. Jeng. Factors affecting serum concentration of dabigatran in Asian patients with non-valvular atrial fibrillation, Journal of the Formosan Medical Association, 2019, 118 (7): 1154-1160.

60. M.-R. Lee, H.-L. Huang, S.-W. Lin, M.-H. Cheng, Y.-T. Lin, S.- Y. Chang, B.-S. Yan, C.-H. Kuo, P.-L. Lu, J.-Y. Wang*, I.-W. Chong. Isoniazid Concentration and NAT2 Genotype Predict Risk of Systemic Drug Reactions during 3HP for LTBI, Journal of Clinical Medicine, 2019, 8(6): 812.

61. M.X. Chen, S.-Y. Wang, C.-H. Kuo, I-L. Tsai*. Metabolome analysis for investigating host-gut microbiota interactions, Journal of the Formosan Medical Association, 2019, 118: S10–S22.

62. C.-H. S.Chen, T.-C. Kuo, H.-C. Kuo, Y. J.Tseng, C.-H. Kuo, T.-H. Yuan, and C.-C. Chan*. Metabolomics of children and adolescents exposed to industrial carcinogenic pollutants, Environmental Science and Technology, 2019, 53(9): 5454-5465.

63. Y.-L. Hsu, C.-C. Chen, Y.-T. Lin, W.-K. Wu, L.-C. Chang, C.-H. Lai, M.-S. Wu, and C.-H. Kuo*. Evaluation and optimization of sample handling methods for quantification of short-chain fatty acids in human fecal samples by GC-MS, Journal of Proteome Research, 2019, 18(5): 1948-1957.

64. K.-P. Chung, G.-Y. Chen, T.-Y. Chuang, Y.-T. Huang, Y.-C. Yeh, H.-T. Chang, Y.-F. Chen, W.-L. Liu, Y.-J. Chen, C.-L. Hsu, M.-T. Huang, C.-H. Kuo *, C.-J. Yu*. Increased plasma acetylcarnitine in sepsis is associated with multi-organ dysfunction and mortality: A multicenter cohort study, Critical Care Medicine, 2018.

65. W.-H. Hsu, Y.-C. Shen, Y.-J. Shiao, C.-H. Kuo, C.-K. Lu, T.-Y. Lin, W.-C. Ku*, Y.-L. Lin*. Combined proteomic and metabolomic analyses of cerebrospinal fluid from mice with ischemic stroke reveals the effects of a Buyang Huanwu decoction in neurodegenerative disease, PLoS One, 2019, 14(1):e0209184.

66. W.-K. Wu, C.-C. Chen, P.-Y. Liu, S. Panyod, B.-Y. Liao, P.-C. Chen, H.-L. Kao, H.-C. Kuo, C.-H. Kuo, T. HT Chiu, R.-A. Chen, H.-L. Chuang, Y.-T. Huang, H.-B. Zou, C.-C. Hsu, T.-Y. Chang, C.-L. Lin, C.-T. Ho, H.-T. Yu, L.-Y. Sheen*, M.-S. Wu*. Identification of TMAO-producer phenotype and host–diet–gut dysbiosis by carnitine challenge test in human and germ-free mice, Gut, 2018; 68(8): 1439-1449.

67. H.-H. Chiu, H.-W. Liao, Y.-Y. Shao, Y.-S. Lu, C.-H. Lin, I-L. Tsai, C.-H. Kuo*. Development of a general method for quantifying IgG-based therapeutic monoclonal antibodies in human plasma using protein G purification coupled with a two internal standard calibration strategy using LC-MS/MS, Analytica Chimica Acta, 2018, 1019: 93-102.

68. P.-S. Wang, C.-H. Kuo, H.-C. Yang, Y.-J. Liang, C.-J. Huang, L.-Y. Sheen*, and W.-H. Pan*. Postprandial Metabolomics Response to Various Cooking Oils in Humans, J. Agric. Food Chem. 2018, 66 (19), pp 4977–4984.

69. H.-W. Liao, S.-W. Lin, Y.-T. Lin, C.-H. Lee, C.-H. Kuo*. Identification of potential sphingomyelin markers for the estimation of hematocrit in dried blood spots via a lipidomic strategy, Analytica Chimica Acta, 2018, 1003: 34-41.

70. C.-L. Tsai, M.-S. Tsai, C.-H. Kuo, T.-H. Chou, W.-J. Chen, C.-H. Huang*. Metabolomic profiling for outcome prediction in emergency department patients without-of-hospital cardiac arrest, Resuscitation, 2018, 123: e1–e2.

71. G.-Y. Chen, H.-C. Chao, H.-W. Liao, I-L. Tsai, Ching-Hua Kuo*. Rapid quantification of glutaminase 2 (GLS2)-related metabolites by HILIC-MS/MS, Analytical Biochemistry, 2017, 539(15): 39-44

72. M.-S. Tsai, S.-Y. Chang, S.-W. Lin, C.-H. Kuo, H.-Y. Sun, B.-R. Wu, S.-Y. Tang, W.-C. Liu, Y.-C. Su, C.-C. Hung*, S.-C. Chang. Treatment response to unboosted atazanavir in combination with tenofovir disoproxil fumarate and lamivudine in human immunodeficiency virus-1-infected patients who have achieved virological suppression: A therapeutic drug monitoring and pharmacogenetic study, Journal of Microbiology, Immunology and Infection, 2017, 50(6), 789-797.

73. I-L. Tsai*, C.-H. Kuo, H.-Y. Sun, Y.-C. Chuang, D. Chepyala, S.-W. Lin, Y.-J. Tsai. An on-spot internal standard addition approach for accurately determining colistin A and colistin B in dried blood spots using ultra high- performance liquid chromatography–tandem mass spectrometry, Journal of Pharmaceutical and Biomedical Analysis, 2017, 145: 783–793.

74. H.-H. Chiu, I-L. Tsai, Y.-S. Lu, C.-H. Lin, C.-H. Kuo*. Development of an LC-MS/MS method with protein G purification strategy for quantifying bevacizumab in human plasma, Analytical and Bioanalytical Chemistry, 2017, 409:6583-6593.

75. W.-H. Jung, C.-C. Liu, Y.-L. Yu, Y.-C. Chang, W.-Y. Lien, H.-C. Chao, S.-Y. Huang, C.-H. Kuo, H.-C. Ho, and C.-C. Chan*. Lipophagy prevents activity-dependent neurodegeneration due to dihydroceramide accumulation in vivo, EMBO Reports, 2017, Article ID: EMBR711.

76. H.-C. Chao, G.-Y. Chen, L.-C. Hsu, H.-W. Liao, S.-Y. Yang, S.-Y. Wang, Y.-L. Li, S.-C. Tang, Y. J. Tseng, C.-H. Kuo*. Using precursor ion scan of 184 with liquid chromatography -electrospray ionization-tandem mass spectrometry for concentration normalization in cellular lipidomic studies, Analytica Chimica Acta, 2017, 971, 68-77.

77. D. Chepya la, I-L. Tsai, H.-W. Liao, G.-Y. Chen, H.-C. Chao, C.-H. Kuo*. Sensitive screening of abused drugs in dried blood samples using ultra-high-performance liquid chromatography-ion booster-quadrupole time-of-flight mass spectrometry (UHPLC-IB-QTOF-MS), Journal of Chromatography A, 2017, 1491( 31) 57-66.

78. Y.-W Tseng, C.-Y. Lin, C.-L. Tsai, T.-Y. Chou, C.-H. Hung, C.-H. Kuo, S.-C. Lai, Y.-J. Tzeng*. Carboxylesterase 2 Is a Fatty Acid Ethyl Ester Synthase, ChemistrySelect, 2017, 2(4):1516–1520.

79. H.-W. Liao, G.-Y. Chen., M.-S. Wu, W.-C. Liao, C.-H. Lin*, and C.-H. Kuo*. Development of a Postcolumn Infused-internal Standard Liquid Chromatography Mass Spectrometry Method for Quantitative Metabolomics Studies, Journal of Proteome Research, 2017, 16 (2), pp 1097–1104.

80. C.-Y. Shen, C.-H. Kuo, S.-Y. Wang, W.-Q. Yang, C.-T. Kuo, Y. J. Tseng*, M.-H. Tsai. Distinct metabolic changes in human lung cancer cells with differential radiation sensitivities, Translational Cancer Research, 2016, 5(6): 738–747.

81. T.-F. Tian, S.-Y. Wang, T.-C. Kuo, C.-E. Tan, G.-Y. Chen, C.-H. Kuo, C.-H. S. Chen, C.-C. Chan, O. A. Lin, Y. J. Tseng. Web Server for Peak Detection, Baseline Correction and Alignment in Two-Dimensional Gas Chromatography Mass Spectrometry-Based Metabolomics Data, Analytical Chemistry, 2016, 88( 21): 10395–10403.

82. H.-W. Liao, S.-W. Lin, G.-Y. Chen, and C.-H Kuo*. Estimation and correction of the blood volume variations of dried blood spots using a postcolumn infused-internal standard strategy with LC-ESI-MS, Analytical Chemistry, 2016, 88 (12): 6457–6464.

83. H.-C. Chao, H.-W. Liao, C.-H Kuo*. Using water plug-assisted analyte focusing by micelle collapse in combination with microemulsion electrokinetic chromatography for analyzing phthalate esters, Journal of Chromatography A, 2016, 1445,149-157.

84. H.-Y. Sun, H.-W. Liao, M.-H. Sheng, H.-M. Tai, C.-H. Kuo, W.-H. Sheng*. Bioequivalence and in vitro antimicrobial activity between generic and brand-name levofloxacin, Diagnostic Microbiology and Infectious Disease, 85 (2016) 347–351.

85. T.-J. Hwang, W.-M. Lo, H.-Y. Chan,C.-F. Lin, M.-H. Hsieh,C.-C. Liu, C.-M. Liu, H.-G. Hwu, C.-H. Kuo, W.-J. Chen*. Fast Versus Slow Strategy of Switching Patients With Schizophrenia to Aripiprazole From Other Antipsychotics, J Clin Psychopharmacol., 2015, 35(6): 635-644.

86. H.-H. Chiu, S.-J. Tsai, Y. J. Tseng, M.-S. Wu, W.-C. Liao, C.-S. Huang*, C.-H. Kuo*. An efficient and robust fatty acid profiling method for plasma metabolomic studies by gas chromatography-mass spectrometry, Clinica Chimica Acta, 2015, 451. 183-190.

87. G.-Y. Chen, H.-W. Liao, I-L. Tsai, Y. J. Tseng, C.-H. Kuo*. Using the Matrix-Induced Ion Suppression Method for Concentration Normalization in Cellular Metabolomics Studies, Analytical Chemistry, 2015, 87(19):9731–9739.(SCI)

88. Lin KY, Liao SH, Liu WC, Cheng A, Lin SW, Chang SY, Tsai MS, Kuo CH, Wu MR, Wang HP, Hung CC, Chang SC. Cholelithiasis and Nephrolithiasis in HIV-Positive Patients in the Era of Combination Antiretroviral Therapy, PLoS ONE, 2015, 10(9): e0137660.(SCI)

89. Lai YS, Chen WC, Kuo TC, Ho CT1, Kuo CH, Tseng YJ, Lu KH, Lin SH, Panyod S, Sheen LY. Mass-Spectrometry-Based Serum Metabolomics of a C57BL/6J Mouse Model of High-Fat-Diet-Induced Non-alcoholic Fatty Liver Disease Development, Journal of agricultural and food chemistry, 2015, 63(35):873–7884.(SCI)

90. Wei-Kai Wu, Suraphan Panyod, Chi-Tang Ho, Ching-Hua Kuo, Ming-Shiang Wu, Lee-Yan Sheen. Dietary allicin reduces transformation of L-carnitine to TMAO through impact on gut microbiota, Journal of Functional Foods, 2015, 15:408-17.(SCI)

91. Wu PF, Lin CH, Kuo CH, Chen WW, Yeh DC, Liao HW, Huang SM, Cheng AL, Lu YS. A pilot study of bevacizumab combined with etoposide and cisplatin in breast cancer patients with leptomeningeal carcinomatosis, BMC Cancer, 2015, 15(1):299.(SCI)

92. Wang SY, Kuo CH, Tseng YJ *. Ion Trace Detection Algorithm to Extract Pure Ion Chromatograms to Improve Untargeted Peak Detection Quality for Liquid Chromatography/Time-of-Flight Mass Spectrometry-Based Metabolomics Data, Analytical Chemistry, 2015 , 87(5):3048-55.(SCI)

93. Guan-yuan Chen, Hsiao-wei Liao, Yufeng Jane Tseng, I-lin Tsai, Ching-hua Kuo*. A matrix-induced ion suppression method to normalize concentration in urinary metabolomics studies using flow injection analysis electrospray ionization mass spectrometry, Analytica Chimica Acta, 2015, 864:21-29.(SCI)

94. D. Chepyala, I-L. Tsai, H.-Y. Sun., S.-W. Lin., C.-H. Kuo*. Development and validation of a high-performance liquid chromatography-fluorescence detection method for the accurate quantification of colistin in human plasma, Journal of Chromatography B, 2015, 980:48-54.(SCI)

95. H.-W. Liao, G.-Y. Chen, M.-S. Wu, W.-C. Liao, I-L. Tsai, C.-H. Kuo*. Quantification of Endogenous Metabolites by the Postcolumn Infused-Internal Standard Method Combined with Matrix Normalization Factor in Liquid Chromatography-electrospray Ionization Tandem Mass Spectrometry, Journal of Chromatography A, 2015, 1375, 62-68.(SCI)

96. H.-Y. Liu, T.-J. Hwang, I-L. Tsai, C.-H. Kuo*. Use of high conductivity sample solution with sweeping-micellar electrokinetic chromatography for trace level quantification of paliperidone in human plasma, Electrophoresis, 2015, 00, 1–9.(SCI)

97. G.-Y. Chen, H.-H Chiu, S.-W. Lin, Y. J. Tseng, S.-J Tsai, and C.-H. Kuo*. Development and application of a comparative fatty acid analysis method to investigate voriconazole-induced hepatotoxicity, Clinica Chimica Acta, 2015, 438, 126-134.(SCI)

98. H.-W. Liao, I-L. Tsai, G.-Y. Chen, Y.-S. Lu C.-H. Lin, C.-H. Kuo*. Quantification of target analytes in various biofluids using a postcolumn infused-internal standard method combined with matrix normalization factors in liquid chromatography–electrospray ionization mass spectrometry, Journal of Chromatography A, 2014, 1358, 85-92.(SCI)

99. H.-W. Liao, G.-Y. Chen, I-L. Tsai, C.-H. Kuo*. Using a Postcolumn-Infused Internal Standard for Correcting the Matrix Effects of Urine Specimens in LC-ESI-MS, Journal of Chromatography A, 2014, 1327, 97-104.(SCI)

100. K.-Y. Lee, S.-W. Lin, H.-Y. Sun, C.-H. Kuo, M-S Tsai, M.-S. Tsai, B.-R. Wu, S.-Y. Tang, W.-C. Liu, S.-Y. Chang*, C.-C. Hung*. Therapeutic Drug Monitoring and Pharmacogenetic Study of HIV-Infected Ethnic Chinese　Receiving Efavirenz-Containing Antiretroviral Therapy with or without Rifampicin-Based Anti-Tuberculous Therapy. PLoS ONE, 2014, 9(2): e88497.(SCI)

101. C.-T. Liu, R. Raghu, S.-H. Lin, S.-Y. Wang, C.-H. Kuo, Y. J. Tseng, and L.-Y. Sheen*. Metabolomics of Ginger Essential Oil against Alcoholic Fatty Liver in Mice, Journal of agricultural and food chemistry, 2013, 61, 11231-11240.(SCI)

102. I-L. Tsai, H.-Y. Sun, G.-Y. Chen, S.-W. Lin, C.-H. Kuo*. Simultaneous quantification of antimicrobial agents for multidrug-resistant bacterial infections in human plasma by ultra-high-pressure liquid chromatography-tandem mass spectrometry, Talanta, 2013, 116, 593-603.(SCI)

103. I-L. Tsai, T-I. Weng, Y. J. Tseng, Happy K.-L. Tan, H.-J. Sun, C.-H. Kuo*. Screening and confirmation of 62 drugs of abuse and metabolites in urine by ultra-high-performance liquid chromatography–quadrupole time-of-flight mass spectrometry, Journal of Analytical Toxicology, 2013, 1-10.(SCI)

104. I-L. Tsai, T.-C. Kuo, T.-J. Ho, Y.-C. Harn, S.-Y. Wang, W.-M. Fu, C.-H. Kuo*, and Y. J. Tseng*. Metabolomic Dynamic Analysis of Hypoxia in MDA-MB-231 and the Comparison with Inferred Metabolites from Transcriptomics Data, Cancers 2013, 5, 491-510.

105. D.-M. Tsai, J.-J. Kang, S.-S. Lee, S.-Y. Wang, I.-L. Tsai, G.-Y. Chen, H.-W. Liao, W.-C. Li, C.-H. Kuo*, and Y.J. Tseng*. Metabolomic Analysis of Complex Chinese Remedies: Examples of Induced Nephrotoxicity in the Mouse from a Series of Remedies Containing Aristolochic Acid, Evidence-Based Complementary and Alternative Medicine, 2013, Article ID 263757.(SCI)

106. H.-W. Liao, I-L. Tsai, G.-Y. Chen, C.-T. Kuo, M.-F. Wei, T.-J. Hwang, W. J. Chen, L.-J. Shen, C.-H. Kuo*. Simultaneous detection of single nucleotide polymorphisms and copy number variations in the CYP2D6 gene by multiplex polymerase chain reaction combined with capillary electrophoresis, Analytica Chimica Acta, 2013, 763: 67-75.(SCI)

107. Y. J. Tseng, C.-T. Kuo, S.-Y. Wang, H.-W. Liao, G.-Y, Chen, Y.-L. Ku, W.-C. Shao, C.-H. Kuo*. Metabolomic characterization of rhubarb species by capillary electrophoresis and ultra-high-pressure liquid chromatography, Electrophoresis, 2013, 34(19):2918-27.(SCI)

108. T.-J. Ho ,C.-H. Kuo, G.-Y. Chen, Y. J. Tseng*. True ion pick (TIPick): a denoising and peak picking algorithm to extract ion signals from liquid chromatography/mass spectrometry data, Journal of Mass Spectrometry, 2013, 48: 234-242.(SCI)

109. S.-Y. Wang, C.-H. Kuo, Y. J. Tseng*. Batch Normalizer, a fast total abundance regression calibration method to simultaneously adjust batch and injection order effects in Liquid Chromatography/Time-of-Flight Mass Spectrometry- Based Metabolomics Data and Comparison with Current Calibration Methods, Analytical Chemistry, 2013, 85: 1037-1046.(SCI)

110. K.-C. Wang, S.-Y. Wang, C.-H. Kuo, Y. J. Tseng*. Distribution-based classification method for baseline correction of metabolomic 1D proton nuclear magnetic resonance spectra. Analytical Chemistry, 2013, 85: 1231-1239.(SCI)

111. H.-H.Lin, S.-A.Chou, H.-Y.Yang, Y.-H Hwang., C.-H. Kuo, T.-W. Kao, T.-C. Lo, P.-C. Chen. Association of blood lead and mercury with estimated GFR in herbalists after the ban of herbs containing aristolochic acids in Taiwan, Occupational and Environmental Medicine, 2013, 70: 545-551.(SCI)

112. M.-L. Li, L.-C. Lee, Y.-R.Cheng, C.H. Kuo, Y.-F. Chou, Y.-S. Chen, C.-M. Yao, P.-R. Chen, C.-J. Hsu, Y.-L. Song *, C.-F. Lee*. A Novel Aerosol-Mediated Drug Delivery System for Inner Ear Therapy: Intratympanic Aerosol Methylprednisolone Can Attenuate Acoustic Trauma, ,IEEE Transactions on Biomedical Engineering, 2013, 60:2450-2460.(SCI)

113. S.-C. Lin, H.-Y. Liu, S.-W. Lin, M. Yao, U.-I. Wu, H.-P. Kuo, C.-H. Kuo*. Simultaneous determination of triazole antifungal drugs in human plasma by sweeping-micellar electrokinetic chromatography, Analytical and Bioanalytical Chemistry, 2012, 404:217-28.(SCI)

114. C.-H. Kuo, K.-C. Wang, T.-F. Tian, M.-H. Tsai, Y.-M. Chiung, C.-M. Hsiech, S.-J. Tsai, S. -Y. Wang, D.-M. Tsai, C.-C. Huang, Y.J. Tseng*. Metabolomic Characterization of Laborers Exposed to Welding Fumes, Chemical Research in Toxicology, 2012, 25: 676–686.(SCI)

115. H.-W. Liao, S.-W. Lin, U.-I. Wu, C.-H. Kuo*. Rapid and sensitive determination of posaconazole in patient plasma by capillary electrophoresis with field-amplified sample stacking, Journal of Chromatography A, 2012, 1226: 48-54.(SCI)

116. I-L. Tsai, H.-Y. Liu, P.-H. Kuo, J.-Y. Wang, C.-H. Kuo*. Quantitative determination of isoniazid in biological samples by Cation Selective Exhaustive Injection-Sweep-Micellar Electrokinetic Chromatography, Analytical and Bioanalytical Chemistry, 2011, 401: 2205-2214.(SCI)

117. W.-C. Chou, K.-Y. Peng, W.-C. Lei, B.-S. Ko, W. Tsay, C.-H. Kuo and H.-F. Tien. Persistence of mutant isocitrate dehydrogenase in patients with acute myeloid leukemia in remission, Leukemia, 2012, 26(3):527-9(SCI)

118. W.-C. Wu; I-L. Tsai; S.-W. Sun; C.-H. Kuo*. Using sweeping-micellar electrokinetic chromatography to determine melamine in food, Food chemistry, 2011, 128: 783-789.(SCI)

119. S.-Y. Wang, T.-J. Ho, C.-H. Kuo*, .Yufeng J. Tseng*. Chromaligner: a web server for chromatogram alignment, Bioinformatics, 2010, 26: 2338-2339.(SCI)

120. S.-C. Lin, S.-W. Lin, J.-M. Chen, C.-H. Kuo*. Using sweeping-micellar electrokinetic chromatography to determine voriconazole in patient plasma, Talanta, 2010, 82; 653-659.(SCI)

121. P.-C. Chiang, S.-C. Lin, S.-L. Pan, C.-H. Kuo, I-L. Tsai, M.-T. Kuo, W.-C.Wen, P. Chen, J.-H. Guh*. A crucial role of AMPK and mTOR pathways, Biochemical Pharmacology, 2010, 79: 162-171.(SCI)

122. C.-H. Kuo*, C.-W. Lee, S.-C. Lin, I-L. Tsai, S.-S. Lee, Y. J. Tseng, J.-J. Kang , F.-C. Peng, W.-C. Li. Rapid determination of aristolochic acids I and II in herbal products and biological samples by ultra-high-pressure liquid chromatography–tandem mass spectrometry, Talanta, 2010, 80: 1672-1680.(SCI)

123. I-L. Tsai, S.-W. Sun, H.-W. Liao, S.-C. Lin, C.-H. Kuo*. Rapid analysis of melamine in infant formula by sweeping-micellar electrokinetic chromatography, Journal of Chromatography A, 2009, 1216: 8296-8303.(SCI)

124. I-L. Tsai, F.-L. L Wu, C.-S. Gau, C.-H. Kuo*. Method development for the determination of teicoplanin in patient serum by solid phase extraction and micellar electrokinetic chromatography, Talanta, 2009, 77: 1208-1216.(SCI)

125. L.-C. Chang, T.-C. Chiu, S.-S. Lee, C.-H. Kuo, T.-C. Chang*. Simultaneous separation of four types of steroid hormones by micellar electrokinetic chromatography with cetyltrimethylammonium bromide, Journal of the Chinese chemical society, 2008; 55: 594-605.(SCI)

126. C.-H. Kuo*, C.-W. Lee , Y.-C. Lai, S.-S. Lee. Determination of oregonin in Alnus plants and biological samples by capillary electrophoresis, Journal of Pharmaceutical and Biomedical Analysis, 2008; 47: 195-200.(SCI)

127. C.-L. Chen, P.-L. Chang, S.-S Lee, F.-C. Peng, C.-H. Kuo*, H.-T. Chang*. Analysis of magnolol and honokiol in biological fluids by capillary zone electrophoresis. Journal of Chromatography A, 2007; 1142:240-244.(SCI)

128. C.-H. Kuo, H.-Y. Chung, S.-W. Sun. Analysis of Lignans Using Micellar Electrokinetic Chromatography, Electrophoresis, 24 (2003) 1047.(SCI)

129. H.-Y. Chang, C.-H. Kuo, S.-W. Sun. Determination of Ursodeoxycholic Acid in Pharmaceutical Preparations by Capillary Electrophoresis with Indirect UV Detection, J. Pharm. Biomed. Anal., 32 (2003) 949.(SCI)

130. C.-H. Kuo, S.-W. Sun. Analysis of Nine Rhubarb Anthraquinones and Bianthrones by Micellar Electrokinetic Chromatography Using Experimental Design, Analytica Chimica Acta, 482 (2003) 47.(SCI)

131. C.-H. Kuo, S.-W. Sun. Separation of Bisbenzylisoquinoline Alkaloids by Micellar Electrokinetic Chromatography, Phytochem. Anal., 13 (2002) 63.(SCI)

132. S.-W. Sun, C.-H. Kuo. Determination of Bisbenzylisoquinoline Alkaloids by High Performance Liquid Chromatography (II), J. Chromatogr. A, 891 (2000) 189.(SCI)