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BLAST home page
http://www.ncbi.nlm.nih.gov/BLAST/
Washington University BLAST (WU-BLAST)
http://blast.wustl.edu/
GSC BLAST Search Service
http://genome.wustl.edu/blast/client.pl
Washington University Genome Sequence
Center
http://www.genome.wustl.edu
Sanger Institute Sequencing Projects
Blast Search Services
http://www.sanger.ac.uk/DataSearch
ProFound,
Protein Identification by Comparison of a Peptide Map to
NCBI’s NR Database
http://prowl.rockefeller.edu/cgi-bin/ProFound
ExPASy
Proteomics Tools
http://www.expasy.ch/tools/
Protein Information Resource
http://pir.georgetown.edu/
ClustalW,
General Purpose Multiple Sequence Alignment Program for DNA or Proteins
http://www.ebi.ac.uk/clustalw
TreeView
for Displaying Phylogenies
http://taxonomy.zoology.gla.ac.uk/rod/treeview.html
PHYLIP for Inferring Phylogenies
http://evolution.genetics.washington.edu/phylip.html
Web Version of PHYLIP
http://biocore.unl.edu/WEBPHYLIP/
PAUP, Tools for Inferring and Interpreting
Phylogenetic Trees
http://paup.csit.fsu.edu/
Genome of Prominent Organisms
http://www.ncbi.nlm.nih.gov/PMGifs/Genomes/org.html.
Complete Genome of Escherichia
coli K12
http://www.ncbi.nlm.nih.gov/genomes//framik.cgi?db=G&gi=115
ProSAL,
Protein Sequence Analysis Launcher
http://xray.bmc.uu.se/sbnet/prosal.html
META-PP, Meta Server for Protein
Prediction
http://maple.bioc.columbia.edu/pp/submit_meta.html
JPred,
Consensus Protein Secondary Structure Prediction
http://www.compbio.dundee.ac.uk/~www-jpred/
PSI-pred,
Protein Structure Prediction Server
http://bioinf.cs.ucl.ac.uk/psipred/psiform.html
PHD, The
Predict Protein Server, Service for Sequence Analysis and Structure Prediction
http://cubic.bioc.columbia.edu/pp
Sspro,
Server for Protein Secondary Structure Prediction based on en ensemble of
11 BRNNs (bidirectional recurrent neural networks)
http://www.igb.uci.edu/tools/scratch/
PROF, Secondary Structure Prediction
http://www.aber.ac.uk/~phiwww/prof/index.html
SDSC1, SDSC Protein Structure Homology
Modeling Server
http://cl.sdsc.edu/hm.html
CPHmodels,
Prediction of Protein Structure
http://www.cbs.dtu.dk/services/CPHmodels/
SWISS-MODEL, Automated Comparative
Protein Modeling Server
http://www.expasy.ch/swissmod/SWISS-MODEL.html
ModBase,
Database of Comparative Protein Structure Models
http://alto.compbio.ucsf.edu/modbase-cgi/index.cgi
LOOPP (Learning, Observing and
Outputting, Protein Patterns), Program for Potential Optimization and Alignment
http://ser-loopp.tc.cornell.edu/loopp.html
Superfamily,
Hidden Markov Model Library and Genome Assignments Server
http://supfam.mrc-lmb.cam.ac.uk/SUPERFAMILY/
The Sausage Machine
(server currently not available)
http://www.zbh.uni-hamburg.de/mitarbeiter/torda.htm
Meta Server, Protein Structure
Prediction
http://bioinfo.pl/Meta/
UCLA/DOE Fold Server, Protein Structure
Assignment Based on Sequence-Derived Properties (SDP)
http://fold.doe-mbi.ucla.edu/
DAS (Dense Alignment Surface method),
Transmembrane Alpha-helices Prediction Server
http://www.sbc.su.se/~miklos/DAS/
TMHMM Server, Prediction of
Transmembrane Helices in Proteins
http://www.cbs.dtu.dk/services/TMHMM-2.0/
TopPred2, Topology Prediction of
Membrane Proteins
http://www.sbc.su.se/~erikw/toppred2/
MOMENT, Transmembrane
Helix Prediction
http://www.doe-mbi.ucla.edu/Services/moment/
Pfam,
Sequence Analysis Server
http://pfam.wustl.edu/hmmsearch.shtml
InterProScan,
Protein Function and Structure Prediction
http://www.ebi.ac.uk/interpro/scan.html
ProDom,
Protein Domain Database
http://prodes.toulouse.inra.fr/prodom/current/html/home.php
BLOCKS, Block Searcher
http://blocks.fhcrc.org/blocks_search.html
SMART (Simple Modular Architecture
Research Tool), Sequence and Architecture Analyses
http://smart.embl-heidelberg.de/
DomFish
(Domain Fishing), Finding Domains in Protein Sequences and Analysis
http://www.bmm.icnet.uk/~3djigsaw/dom_fish/
Database of Protein Family and
Domains
http://tw.expasy.ch/prosite/
eMOTIF,
Database of Highly Specific and Sensitive Protein Sequence Motifs Representing
Conserved Biochemical Properties and Biological Functions
http://dna.stanford.edu/identify
GeneQuiz,
Highly Automated Analysis of Biological Sequences
http://jura.ebi.ac.uk:8765/ext-genequiz/
PRINTS, Compendium of Protein Fingerprints,
Conserved Motifs Used to Characterise a Protein
Family
http://bioinf.man.ac.uk/dbbrowser/PRINTS/PRINTS.html
P-val
FPScan, Scan PRINTS with a query sequence
http://bioinf.man.ac.uk/cgi-bin/dbbrowser/fingerPRINTScan/muppet/FPScan.cgi
SignalP,
Server Predicting the Presence and Location of Signal Peptide Cleavage Sites
in Amino Acid Sequences
http://www.cbs.dtu.dk/services/SignalP/
PsortII,
Prediction of Protein Localization Sites in Cells
http://psort.nibb.ac.jp/form2.html
ChloroP,
Server Predicting the Presence of Chloroplast Transit Peptides (cTP)
in Protein Sequences and the Location of Potential
cTP Cleavage Sites.
http://www.cbs.dtu.dk/services/ChloroP/
ExPASy
(Expert Protein
Analysis System),
Proteomic Server
http://www.expasy.ch/
NetPhos,
Neural Network Predictions for Serine, Threonine
and Tyrosine Phosphorylation Sites in Eukaryotic
Proteins
http://www.cbs.dtu.dk/services/NetPhos/
NetPicoRNA,
Prediction of Picornavirus Protease Sites
http://www.cbs.dtu.dk/services/NetPicoRNA/
CASP (Critical Assessment of Techniques
for Protein Structure Prediction), Protein Structure Prediction Center
http://predictioncenter.llnl.gov/
CAFASP (Critical Assessment of
Fully Automated Structure Prediction), Main Data Management Site for Tertiary
Structure Prediction
http://bioinfo.pl/cafasp/
LiveBench,
Continuous Benchmarking of Structure Prediction
Servers
http://bioinfo.pl/LiveBench/
SCOP ( Structural
Classification of Proteins)
http://scop.berkeley.edu
BIND (The
Biomolecular Interaction Network Database)
http://www.bind.ca/
BRITE (Biomolecular
Relations in Information Transmission and Expression)
http://www.genome.ad.jp/brite/
DIP (Database of Interacting Proteins),
Database cataloging Experimentally Determined Interactions
Between Proteins
http://dip.doe-mbi.ucla.edu/
DPInteract,
Database on DNA-Protein Interactions
http://arep.med.harvard.edu/dpinteract/
UMBER (University of Manchester
Bioinformatics Education and Research),
Visualisation
representing All of the Proteins in the Database and Their Interactions
http://www.bioinf.man.ac.uk/resources/interact.shtml
LIGAND, Database of Chemical Compounds
and Reactions in Biological Pathways
http://www.genome.ad.jp/dbget/ligand.html
MINT (Molecular Interaction Database),
Database Designed to Store Functional Interactions between Biological Molecules
http://cbm.bio.uniroma2.it./mint/
CYGD (Comprehensive Yeast Genome
Database), Genome for the budding Yeast Saccharomyces
cerevisiae
http://mips.gsf.de/proj/yeast/CYGD/db/index.html
REBASE (The Restriction Enzyme
Database), Collection of Information about Restriction Enzymes and Related
Proteins
http://rebase.neb.com/rebase/rebase.html
RegulonDB,
Database on Transcriptional Regulation and Operon
Organization
http://www.cifn.unam.mx/Computational_Genomics/regulondb/
ReLiBase,
Web-Based Tool for Searching and Analysing Receptor
Ligand Structures in the PDB
http://www.ccdc.cam.ac.uk/prods/relibase
TRANSFAC, The
Transcription Factor Database
http://transfac.gbf.de/TRANSFAC/
TRRD, Transcription Regulatory
Region Database
http://wwwmgs.bionet.nsc.ru/mgs/dbases/trrd4/
PIMRider®,
Hybrigenics' New Functional Proteomics Software
Platform, Dedicated to the Exploration of Protein Pathways
http://pim.hybrigenics.com/pimrider/pimriderlobby/PimRiderLobby.jsp
BioCarta,
Functional Proteomics Service
http://www.biocarta.com/
BRITE
http://www.genome.ad.jp/brite/
BioCyc,
Knowledge Library of Pathways and Genomes
http://biocyc.org/
EMP Project, Enzymes and Metabolic
Pathways Database
http://www.empproject.com/
GeneNet, Meta-Search System for the Analysis of Sequence Similarity
http://brac.postech.ac.kr/eng/
KEGG (
Kyoto
Encyclopedia of Genes and Genomes), Bioinformatics Resource for Understanding
Higher Order Functional Meanings and Utilities of the Cell or the Organism
from Its Genome Information
http://www.genome.ad.jp/kegg/
LIGAND
http://www.genome.ad.jp/dbget/ligand.html
CYGD
http://mips.gsf.de/proj/yeast/CYGD/db/index.html
PFBP ( Protein
Function and Biochemical Pathways), Comprehensive Resource Containing Information
on Organism and Tissue Specific Metabolic and Other Biochemical Pathways
http://www.ebi.ac.uk/research/pfbp/
RegulonDB
http://www.cifn.unam.mx/Computational_Genomics/regulondb/
STKE (Signal Transduction Knowledge
Environment)
http://stke.sciencemag.org/
TRRD4
http://wwwmgs.bionet.nsc.ru/mgs/dbases/trrd4/
WIT, Curation
of Function Assignments Made to Genes and the Development of Metabolic Models
http://wit.mcs.anl.gov/WIT2/
dbEST,
Expressed Sequence Tags database
http://www.ncbi.nlm.nih.gov/dbEST/index.html
SAGE (Serial Analysis of Gene Expression)
http://www.ncbi.nlm.nih.gov/SAGE/
UniGene,
Experimental
System for Automatically Partitioning GenBank
Sequences into a Non-Redundant Set of Gene-Oriented Clusters
http://www.ncbi.nlm.nih.gov/UniGene/
SMD (Stanford
Microarray Database), Storing Raw and Normalized
Data from Microarray Experiments and Their Corresponding
Image Files
http://genome-www5.stanford.edu/MicroArray/SMD/
SWISS-2DPAGE, Two-Dimensional
Polyacrylamide Gel Electrophoresis Database
http://tw.expasy.org/ch2d/
SGD (Saccharomyces
Genome Database), Scientific Database of the Molecular Biology and Genetics
of the Yeast Saccharomyces
cerevisiae ( baker's
or budding yeast)
http://genome-www.stanford.edu/Saccharomyces/
PLEX (Protein Link Explorer), Constructing
Phylogenetic Profiles and
Searching for Gene Neighbors
of All the Proteins Whose Profiles Match a Given Protein
http://apropos.icmb.utexas.edu/function-prediction.html
CAFASP
http://bioinfo.pl/cafasp/
SWISS-2DPAGE
http://tw.expasy.org/ch2d/
SWISS-PROT, Protein Knowledgebase
http://tw.expasy.org/sprot/
BRENDA, The Comprehensive Enzyme
Information System
http://www.brenda.uni-koeln.de/
EVA summary for category
sec(1)
http://cubic.bioc.columbia.edu/eva/sec/common.html
EVA (EValuation
of Automatic protein structure)
http://cubic.bioc.columbia.edu/eva/index.html
DIP
http://dip.doe-mbi.ucla.edu/
FlyBase,
Drosophilia Genome Database
http://flybase.bio.indiana.edu/
SMD
http://genome-www5.stanford.edu/cgi-bin/SMD/login.pl
SGD
http://genome-www.stanford.edu/Saccharomyces/
META-PP
http://maple.bioc.columbia.edu/pp/submit_meta.html
SnapDRAGON,
Protein Domain Boundary Prediction
http://mathbio.nimr.mrc.ac.uk/~rgeorge/snapdragon/
NEXTDB (The Nematode Expression
Pattern DataBase)
http://nematode.lab.nig.ac.jp/
Pfam
http://pfam.wustl.edu/hmmsearch.shtml
ModBase
http://alto.compbio.ucsf.edu/modbase-cgi/index.cgi
CASP
http://predictioncenter.llnl.gov/
ProDom
http://prodes.toulouse.inra.fr/prodom.html
PSort
http://psort.nibb.ac.jp/
Eisen
Lab Software
http://rana.lbl.gov/EisenSoftware.htm
SCOP
http://scop.berkeley.edu
SMART
http://smart.embl-heidelberg.de/
TRANSFAC
http://transfac.gbf.de/TRANSFAC
WIT
http://wit.mcs.anl.gov/WIT2/
ProSal
http://xray.bmc.uu.se/sbnet/prosal.html
BIND
http://www.bind.ca/
CATH (Class, Architecture, Topology,
Homolgoues Superfamily),
Novel Hierarchical Classification of Protein Domain Structures
http://www.biochem.ucl.ac.uk/bsm/cath/
BLOCKS
http://www.blocks.fhcrc.org/blocks_search.html
DomFish
http://www.bmm.icnet.uk/~3djigsaw/dom_fish/
STRING (Search
Tool for the Retrieval of Interacting Genes/Proteins)
http://www.bork.embl-heidelberg.de/STRING/
SignalP
http://www.cbs.dtu.dk/services/SignalP/output.html
RegulonDB
http://www.cifn.unam.mx/Computational_Genomics/regulondb/
AxelDB,
Database Focussing on Gene Expression in the
Frog Xenopus
laevis
http://www.dkfz-heidelberg.de/abt0135/axeldb.htm
MOMENT
http://www.doe-mbi.ucla.edu/Services/moment/
FSSP (Fold
classification based on Structure-Structure alignment of Proteins)
http://www2.ebi.ac.uk/dali/fssp/fssp.html
SWISS-MODEL
http://www.expasy.ch/swissmod/SWISS-MODEL.html
SBASE, Protein Domain Library
http://hydra.icgeb.trieste.it/~kristian/SBASE/
Incite Proteome
BioKnowledge®
Library
http://www.incyte.com/sequence/proteome/index.shtml
MGI (Mouse Genome Informatics)
http://www.informatics.jax.org/
NCBI (National Center for Biotechnology
Information)
http://www.ncbi.nlm.nih.gov
BLAST
http://www.ncbi.nlm.nih.gov/BLAST/
COG ( Clusters
of Orthologous Groups of proteins)
http://www.ncbi.nlm.nih.gov/COG/
BLAST Information Guide
http://www.ncbi.nlm.nih.gov/Education/BLASTinfo/information3.html
Prominent Organisms
http://www.ncbi.nlm.nih.gov/PMGifs/Genomes/org.html
DGS (Domain Guess by Size), Guess
at the Most Likely Locations of Protein Domain Boundaries
http://www.ncbi.nlm.nih.gov/Structure/dgs/DGSWeb.cgi
Protein Data Bank
http://www.rcsb.org
Global
Transposon Mutagenesis and a Minimal
Mycoplasma Genome
http://www.sciencemag.org/feature/data/1042937.shl
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